The Lexus LS 460h easily outscored the Mercedes S550 in CR's tests of the ultra-luxury cruisers. Both cars provide the highest levels of comfort, quietness, roominess, and luxury features. The Mercedes had more agile handling, better steering feel, and a slight edge in ride comfort and acceleration. But its score was hurt by its much lower fuel economy (21 mpg in the Lexus vs. 17 mpg in the Mercedes) and complicated controls that can be frustrating to use

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