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From outside, there seems to be no change to Mercedes-Benz's mid-size, mid-level six-cylinder E Class sedan for 2006. Looking closer, the name has changed, from E320 to E350. That seemingly small change makes a major difference. Important changes to the engine and a seven-speed automatic transmission add power and refinement to a car that has long been a benchmark in the mid-luxury class, with no decrease in fuel economy.

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